RORB antibody (C-Term)

Catalog No. ABIN2780814

This Rabbit Polyclonal antibody specifically detects RORB in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Sheep, Rabbit and Guinea Pig.

Quick Overview for RORB antibody (C-Term) (ABIN2780814)

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Sheep, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RORB antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RORB Antibody

Binding Specificity: C-Term

Sequence: KNHLDDETLA KLIAKIPTIT AVCNLHGEKL QVFKQSHPEI VNTLFPPLYK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Characteristics: This is a rabbit polyclonal antibody against RORB. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RORB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 459 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RORB

Target: RORB (RAR-Related Orphan Receptor B (RORB))

Alternative Name: RORB

Background: RORB is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation. The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NR1F2, ROR-BETA, RZRB, bA133M9.1, RZR-BETA
Protein Interaction Partner: NSD1, NCOA1, NCOA6, PNRC1, EIF3I, NRIP1, UBE2I, TNNI2, SRC, PSMC4, NPPA, MAP6, PNRC2, NRIP2, NME2, NME1,
Protein Size: 459

Molecular Weight: 52 kDa

Gene ID: 6096

NCBI Accession: NM_006914, NP_008845

UniProt: Q98934

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway