KLF12 antibody (N-Term)

Catalog No. ABIN2780839

This Rabbit Polyclonal antibody specifically detects KLF12 in WB. It exhibits reactivity toward Human, Dog, Guinea Pig and Rabbit.

Quick Overview for KLF12 antibody (N-Term) (ABIN2780839)

Target: KLF12 (Kruppel-Like Factor 12 (KLF12))

Reactivity: Human, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLF12 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KLF12 Antibody

Binding Specificity: N-Term

Sequence: NIHMKRKTIK NINTFENRML MLDGMPAVRV KTELLESEQG SPNVHNYPDM

Predicted Reactivity: Dog: 100%, Guinea Pig: 93%, Human: 100%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against KLF12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KLF12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 402 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KLF12

Target: KLF12 (Kruppel-Like Factor 12 (KLF12))

Alternative Name: KLF12

Background: Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. KLF12 is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1.Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. The protein encoded by this gene is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AP-2rep, AP2REP, HSPC122
Protein Interaction Partner: THAP1, CTBP1, APP, EHMT2,
Protein Size: 402

Molecular Weight: 44 kDa

Gene ID: 11278

NCBI Accession: NM_007249, NP_009180

UniProt: Q9Y4X4