CBX6 antibody (C-Term)

Catalog No. ABIN2780919

The Rabbit Polyclonal anti-CBX6 antibody has been validated for WB. It is suitable to detect CBX6 in samples from Human, Mouse, Rat, Dog, Cow, Horse and Guinea Pig.

Quick Overview for CBX6 antibody (C-Term) (ABIN2780919)

Target: CBX6 (Chromobox Homolog 6 (CBX6))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CBX6 Antibody

Binding Specificity: C-Term

Sequence: SAATSKRAPP EVTAAAGPAP PTAPEPAGAS SEPEAGDWRP EMSPCSNVVV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against CBX6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CBX6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 412 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CBX6

Target: CBX6 (Chromobox Homolog 6 (CBX6))

Alternative Name: CBX6

Background: CBX6 is involved in maintaining the transcriptionally repressive state of genes. It modifies chromatin, rendering it heritably changed in its expressibility.
Protein Interaction Partner: RNF2, LYN, TOPAZ1, CCDC158, PCGF1, PCGF5, PCGF6, LAS1L, KRI1, RNF213, RGAG1, ZKSCAN7, DACT1, AHDC1, ELP4, KHDRBS1, IGF2BP2, IGF2BP3, IGF2BP1, PAIP1, PCGF3, CEP350, ULK2, UBC, CEP135, NCOR2, ZMYM4, HIST2H2BE, HIST1H2AB, HIST3H3, CHAF1B, PCGF2, ZNF33A, SSB,
Protein Size: 412

Molecular Weight: 44 kDa

Gene ID: 23466

NCBI Accession: NM_014292, NP_055107

UniProt: O95503