OTX1 antibody (N-Term)

Catalog No. ABIN2780931

Product Details anti-OTX1 Antibody

Target: OTX1 (Orthodenticle Homeobox 1 (OTX1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Cow, Zebrafish (Danio rerio), Guinea Pig, Horse, Rabbit, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OTX1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: PRKQRRERTT FTRSQLDVLE ALFAKTRYPD IFMREEVALK INLPESRVQV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against OTX1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human OTX1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 354 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for OTX1

Target: OTX1 (Orthodenticle Homeobox 1 (OTX1))

Alternative Name: OTX1 (OTX1 Products)

Background: OTX1 probably plays a role in the development of the brain and the sense organs. OTX1 can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.
Alias Symbols: FLJ38361, MGC15736
Protein Interaction Partner: KRTAP10-3, KRTAP10-8, KRTAP10-5, KRTAP10-11, KRTAP10-1, KRTAP10-9, KRTAP12-2, LCE2D, LCE2A, LCE1B, LCE4A, MGAT5B, KRTAP3-3, KRTAP4-2, KRTAP4-7, KRTAP9-4, KRTAP9-2, KRTAP4-11, GEMIN8P4, KRTAP5-6, KRTAP26-1, KRTAP12-4, KRTAP3-2, KCNK16, KRTAP4-12, RGS17, RB
Protein Size: 354

Molecular Weight: 37 kDa

Gene ID: 5013

NCBI Accession: NM_014562, NP_055377

UniProt: P32242