RNF149 antibody (C-Term)

Catalog No. ABIN2781275

This anti-RNF149 antibody is a Rabbit Polyclonal antibody detecting RNF149 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit and Guinea Pig.

Quick Overview for RNF149 antibody (C-Term) (ABIN2781275)

Target: RNF149 (Ring Finger Protein 149 (RNF149))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNF149 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RNF149 Antibody

Binding Specificity: C-Term

Sequence: LLHTVKHGEK GIDVDAENCA VCIENFKVKD IIRILPCKHI FHRICIDPWL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RNF149. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human RNF149

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RNF149

Target: RNF149 (Ring Finger Protein 149 (RNF149))

Alternative Name: RNF149

Background: RNF149 is a E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation.
Alias Symbols: DNAPTP2
Protein Interaction Partner: UBC, ELAVL1, BRAF,
Protein Size: 400

Molecular Weight: 43 kDa

Gene ID: 284996

NCBI Accession: NM_173647, NP_775918

UniProt: Q8NC42