ABCB9 antibody (N-Term)

Catalog No. ABIN2781527

This anti-ABCB9 antibody is a Rabbit Polyclonal antibody detecting ABCB9 in WB. Suitable for Human, Mouse, Rat, Pig, Cow, Dog, Guinea Pig and Rabbit. This Primary Antibody has been cited in 1 publication.

Quick Overview for ABCB9 antibody (N-Term) (ABIN2781527)

Target: ABCB9 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 9 (ABCB9))

Reactivity: Human, Mouse, Rat, Pig, Cow, Dog, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCB9 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ABCB9 Antibody

Binding Specificity: N-Term

Sequence: RLWKAVVVTL AFMSVDICVT TAIYVFSHLD RSLLEDIRHF NIFDSVLDLW

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 75%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ABCB9. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ABCB9

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 723 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ABCB9 antibody (ABIN2781527)

Mattern, Raikar, Hardin: "The effect of caveolin-1 (Cav-1) on fatty acid uptake and CD36 localization and lipotoxicity in vascular smooth muscle (VSM) cells." in: International journal of physiology, pathophysiology and pharmacology, Vol. 1, Issue 1, pp. 1-14, (2011) (PubMed).

Target Details for ABCB9

Target: ABCB9 (ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 9 (ABCB9))

Alternative Name: ABCB9

Background: ABCB9, a membrane-associated protein, is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABCB9 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined, however, this protein may play a role in lysosomes.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined, however, this protein may play a role in lysosomes. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specifications.
Alias Symbols: EST122234, KIAA1520, TAPL
Protein Interaction Partner: UBC,
Protein Size: 723

Molecular Weight: 80 kDa

Gene ID: 23457

NCBI Accession: NM_019624, NP_062570

UniProt: Q9NP78

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process