SLC39A4 antibody (N-Term)

Catalog No. ABIN2781713

This anti-SLC39A4 antibody is a Rabbit Polyclonal antibody detecting SLC39A4 in WB. Suitable for Human, Rabbit and Cow. This Primary Antibody has been cited in 1 publication.

Quick Overview for SLC39A4 antibody (N-Term) (ABIN2781713)

Target: SLC39A4 (Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4))

Reactivity: Human, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC39A4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SLC39A4 Antibody

Binding Specificity: N-Term

Sequence: ASLVSLELGL LLAVLVVTAT ASPPAGLLSL LTSGQGALDQ EALGGLLNTL

Predicted Reactivity: Cow: 86%, Human: 100%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against SLC39A4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC39A4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 647 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-SLC39A4 antibody (ABIN2781713)

Antala, Ovchinnikov, Kamisetty, Baker, Dempski: "Computation and Functional Studies Provide a Model for the Structure of the Zinc Transporter hZIP4." in: The Journal of biological chemistry, Vol. 290, Issue 29, pp. 17796-805, (2015) (PubMed).

Target Details for SLC39A4

Target: SLC39A4 (Solute Carrier Family 39 (Zinc Transporter), Member 4 (SLC39A4))

Alternative Name: SLC39A4

Background: SLC39A4 is a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in the gene encoding SLC39A4 result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc.This gene encodes a member of the zinc/iron-regulated transporter-like protein (ZIP) family. The transmembrane protein is required for zinc uptake in the intestine. Mutations in this gene result in acrodermatitis enteropathica, a rare inherited defect in the absorption of dietary zinc. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AEZ, FLJ20327, MGC74741, ZIP4, AWMS2
Protein Interaction Partner: UBC,
Protein Size: 647

Molecular Weight: 68 kDa

Gene ID: 55630

NCBI Accession: NM_130849, NP_570901

UniProt: Q6P5W5

Pathways: Transition Metal Ion Homeostasis, Autophagy