RRBP1 antibody (N-Term)

Catalog No. ABIN2782077

The Rabbit Polyclonal anti-RRBP1 antibody has been validated for WB. It is suitable to detect RRBP1 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit and Horse.

Quick Overview for RRBP1 antibody (N-Term) (ABIN2782077)

Target: RRBP1 (Ribosome Binding Protein 1 (RRBP1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RRBP1 Antibody

Binding Specificity: N-Term

Sequence: TDVAQSPEAP KQEAPAKKKS GSKKKGPPDA DGPLYLPYKT LVSTVGSMVF

Predicted Reactivity: Cow: 82%, Dog: 81%, Guinea Pig: 76%, Horse: 92%, Human: 100%, Mouse: 75%, Rabbit: 81%, Rat: 82%

Characteristics: This is a rabbit polyclonal antibody against RRBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RRBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 977 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RRBP1

Target: RRBP1 (Ribosome Binding Protein 1 (RRBP1))

Alternative Name: RRBP1

Background: Analysis of cDNA clones indicates that ribosome binding protein 1 may exist in different forms due to removal of tandem repeats, or partial intraexonic splicing of RRBP1. The form presented here is lacking the canine p180 ribosome-binding domain, NQGKKAEGAQ, which is tandemly repeated close to the N-terminus in other forms that haven't been fully characterized. RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome.Analysis of cDNA clones indicates that ribosome binding protein 1 may exist in different forms due to removal of tandem repeats, or partial intraexonic splicing of RRBP1. The form presented here is lacking the canine p180 ribosome-binding domain, NQGKKAEGAQ, which is tandemly repeated close to the N-terminus in other forms that haven't been fully characterized. RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome. Alternate splicing results in multiple transcript variants.
Alias Symbols: DKFZp586A1420, ES/130, ES130, FLJ36146, MGC157720, MGC157721, hES, RRp
Protein Interaction Partner: VCP, UBC, MDM2, LGR4, TARDBP, IQCB1, MAP1LC3A, PRKD2, SMAD9, MRPL53, SRPRB, CDV3, CHMP2A, PPIF, PQBP1, SCP2, RPS19, RPL38, RBMS1, PIN4, NDUFA7, HNRNPM, RAB8A, ILF3, HSPA1L, HSBP1, KLF5, CUL3, KIAA0101, SUMO1, Ndc80, ZWINT, ATF7IP, KIF5B, DSTN,
Protein Size: 977

Molecular Weight: 109 kDa

Gene ID: 6238

NCBI Accession: NM_001042576, NP_001036041