Ribophorin II antibody (N-Term)

Catalog No. ABIN2782203

This Rabbit Polyclonal antibody specifically detects Ribophorin II in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Cow, Pig and Rabbitand has been mentioned in 1 publication.

Quick Overview for Ribophorin II antibody (N-Term) (ABIN2782203)

Target: Ribophorin II (RPN2)

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ribophorin II antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Ribophorin II Antibody

Binding Specificity: N-Term

Sequence: ASQEALSALT ARLSKEETVL ATVQALQTAS HLSQQADLRS IVEEIEDLVA

Predicted Reactivity: Cow: 93%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RPN2. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RPN2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 631 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-Ribophorin II antibody (ABIN2782203)

Fujimoto, Goi, Hirono: "Expression of ribophorine II is a promising prognostic factor in human gastric adenocarcinoma." in: International journal of oncology, Vol. 50, Issue 2, pp. 448-456, (2016) (PubMed).

Target Details for Ribophorin II

Target: Ribophorin II (RPN2)

Alternative Name: RPN2

Background: RPN2 is a type I integral membrane protein found only in the rough endoplasmic reticulum. The protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains.This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein is similar in sequence to the yeast oligosaccharyl transferase subunit SWP1.
Alias Symbols: RIBIIR, RPN-II, RPNII, SWP1
Protein Interaction Partner: UBC, FUS, FAF1, VAPB, EED, ADRB2, CLN3, MMS19, RCHY1, UBL4A, ESR1, RHOA, RPN1, ILF3, PDIA3, CANX, ATP5A1, STT3B, TM9SF2, FBXO6, CUL3, FBXO25, SIRT7, TCF3, AUP1, ARRB2, NDRG1, SUMO2, FBN3, RBBP4, NGFR, HDAC5, MYC, RNF185, H2AFX, BRE, ADRM1, EZH2, GSTK1, TM
Protein Size: 631

Molecular Weight: 69 kDa

Gene ID: 6185

NCBI Accession: NM_002951, NP_002942

UniProt: P04844