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RRP1B antibody (Middle Region)

This Rabbit Polyclonal antibody specifically detects RRP1B in WB. It exhibits reactivity toward Human, Cow, Dog, Guinea Pig, Horse, Rabbit, Mouse and Ratand has been mentioned in 1 publication.
Catalog No. ABIN405769

Quick Overview for RRP1B antibody (Middle Region) (ABIN405769)

Target

RRP1B (Ribosomal RNA Processing 1 Homolog B (RRP1B))

Reactivity

  • 14
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Cow, Dog, Guinea Pig, Horse, Rabbit, Mouse, Rat

Host

  • 14
Rabbit

Clonality

  • 14
Polyclonal

Conjugate

  • 9
  • 1
  • 1
  • 1
  • 1
  • 1
This RRP1B antibody is un-conjugated

Application

  • 14
  • 9
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequence

    VTFGLNRNMT AEFKKTDKSI LVSPTGPSRV AFDPEQKPLH GVLKTPTSSP

    Predicted Reactivity

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

    Characteristics

    This is a rabbit polyclonal antibody against RRP1B. It was validated on Western Blot using a cell lysate as a positive control.

    Purification

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human RRP1B
  • Application Notes

    Optimal working dilutions should be determined experimentally by the investigator.

    Comment

    Antigen size: 758 AA

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Crawford, Qian, Ziogas, Papageorge, Boersma, Walker, Lukes, Rowe, Zhang, Ambs, Lowy, Anton-Culver, Hunter: "Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis." in: PLoS genetics, Vol. 3, Issue 11, pp. e214, (2007) (PubMed).

  • Target

    RRP1B (Ribosomal RNA Processing 1 Homolog B (RRP1B))

    Alternative Name

    RRP1B

    Background

    RRP1B belongs to the RRP1 family. It may be a novel susceptibility gene for breast cancer progression and metastasis.
    Alias Symbols: KIAA0179, Nnp1, RRP1, NNP1L
    Protein Interaction Partner: TP53, UBC, TARBP2, RNF2, LSM1, SRPK3, MAPK14, CSNK2A2, MPG, PPP1CA, CSNK2A1, APOA1, PPP1CC, ESR1, CUL3, SIRT7, ELAVL1, SUMO2, HDGF, SUMO1, RPL10A, NCL, ILF3, IGKC, HNRNPA1, PARP1, Rrp1b, SLC22A11, LUC7L3, LUC7L2, IGKV2-40, RSL1D1, SDF2L1, LARP1, ALYREF, D
    Protein Size: 758

    Molecular Weight

    84 kDa

    Gene ID

    23076

    NCBI Accession

    NM_015056, NP_055871

    UniProt

    Q14684
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