CTP Synthase antibody (N-Term)

Catalog No. ABIN310762

This Rabbit Polyclonal antibody specifically detects CTP Synthase in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for CTP Synthase antibody (N-Term) (ABIN310762)

Target: CTP Synthase (CTPS)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTP Synthase antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-CTP Synthase Antibody

Binding Specificity: N-Term

Sequence: SMPFIEAFRQ FQFKVKRENF CNIHVSLVPQ PSSTGEQKTK PTQNSVRELR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against CTPS. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CTPS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 591 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CTP Synthase

Target: CTP Synthase (CTPS)

Alternative Name: CTPS

Background: The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis.The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types.The catalytic conversion of UTP to CTP is accomplished by the enzyme cytidine-5-prime-triphosphate synthetase. The enzyme is important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types.
Alias Symbols: CTPS
Protein Interaction Partner: UBC, CTPS1, TUBGCP3, AURKA, SUMO2, SUMO3, SUMO1, NEDD8, DCTPP1, GINS3, UBA6, UBXN1, PAPSS1, VCL, UBA1, PPP5C, PKM, DFFA, CS, CLNS1A, ACO1, YWHAQ, MYC, RBM28, POLR1C, FBXO6, CAND1, COPS5, CUL1, CUL2, CUL3, CUL4B, CUL5, CDK2, ARRB2, RAD21, PSMA3, YWHAG, TRA
Protein Size: 591

Molecular Weight: 67 kDa

Gene ID: 1503

NCBI Accession: NM_001905, NP_001896

UniProt: P17812

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process