PIGQ antibody (N-Term)
Quick Overview for PIGQ antibody (N-Term) (ABIN2782619)
Target
See all PIGQ AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Sequence
- VLHFPFIPIQ VKQLLAQVRQ ASQVGVAVLG TWCHCRQEPE ESLGRFLESL
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Predicted Reactivity
- Cow: 92%, Guinea Pig: 83%, Horse: 85%, Human: 100%, Mouse: 83%, Pig: 92%, Rabbit: 85%, Rat: 92%
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Characteristics
- This is a rabbit polyclonal antibody against PIGQ. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PIGQ
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 760 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PIGQ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Q (PIGQ))
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Alternative Name
- PIGQ
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Background
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PIGQ is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGQ is a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI).
Alias Symbols: GPI1, MGC12693, c407A10.1, hGPI1
Protein Interaction Partner: SMAD1, UBC, PIGC, PIGH, PIGA, PIGP,
Protein Size: 760 -
Molecular Weight
- 84 kDa
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Gene ID
- 9091
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NCBI Accession
- NM_148920, NP_683721
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UniProt
- Q9BRB3
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Pathways
- Inositol Metabolic Process
Target
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