PIGQ antibody (N-Term)

Catalog No. ABIN2782620

The Rabbit Polyclonal anti-PIGQ antibody has been validated for WB. It is suitable to detect PIGQ in samples from Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow and Dog.

Quick Overview for PIGQ antibody (N-Term) (ABIN2782620)

Target: PIGQ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Q (PIGQ))

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Rabbit, Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PIGQ antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PIGQ Antibody

Binding Specificity: N-Term

Sequence: PTVLPDRQAG ATTASTGGLA AVFDTVARSE VLFRSDRFDE GPVRLSHWQS

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against PIGQ. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PIGQ

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 581 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PIGQ

Target: PIGQ (Phosphatidylinositol Glycan Anchor Biosynthesis, Class Q (PIGQ))

Alternative Name: PIGQ

Background: PIGQ is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGQ is a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI).This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI).
Alias Symbols: GPI1, MGC12693, c407A10.1, hGPI1
Protein Interaction Partner: SMAD1, UBC, PIGC, PIGH, PIGA, PIGP,
Protein Size: 581

Molecular Weight: 65 kDa

Gene ID: 9091

NCBI Accession: NM_004204, NP_004195

UniProt: Q9BRB3

Pathways: Inositol Metabolic Process