Dystroglycan antibody (Middle Region)

Catalog No. ABIN2782634

The Rabbit Polyclonal anti-Dystroglycan antibody has been validated for WB. It is suitable to detect Dystroglycan in samples from Human.

Quick Overview for Dystroglycan antibody (Middle Region) (ABIN2782634)

Target: Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dystroglycan antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Dystroglycan Antibody

Binding Specificity: Middle Region

Sequence: AIGPPTTAIQ EPPSRIVPTP TSPAIAPPTE TMAPPVRDPV PGKPTVTIRT

Predicted Reactivity: Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, African clawed frog : 90 %, Guinea pig : 90 %, Zebrafish : 70 %

Characteristics: This is a rabbit polyclonal antibody against DAG1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human alpha-DAG1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 895 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for Dystroglycan

Target: Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))

Alternative Name: DAG1

Background: Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal

Molecular Weight: 27 kDa

Gene ID: 1605

NCBI Accession: NM_004393, NP_004384

UniProt: Q14118

Pathways: Maintenance of Protein Location, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus