BCAP31 antibody (Middle Region)

Catalog No. ABIN2782693

This Rabbit Polyclonal antibody specifically detects BCAP31 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for BCAP31 antibody (Middle Region) (ABIN2782693)

Target: BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCAP31 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-BCAP31 Antibody

Binding Specificity: Middle Region

Sequence: STKQKLEKAE NQVLAMRKQS EGLTKEYDRL LEEHAKLQAA VDGPMDKKEE

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against BCAP31. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BCAP31

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 246 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BCAP31

Target: BCAP31 (B-Cell Receptor-Associated Protein 31 (BCAP31))

Alternative Name: BCAP31

Background: BCAP31 is a member of the B-cell receptor associated protein 31 superfamily. It is a multi-pass transmembrane protein of the endoplasmic reticulum that is involved in the anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi and in the caspase 8-mediated apoptosis. Microdeletions in this gene are associated with the contiguous ABCD1/DXS1375E deletion syndrome.
Alias Symbols: 6C6-AG, BAP31, CDM, DXS1357E
Protein Interaction Partner: GPRIN2, UBC, COX2, ITGAM, RPA3, RPA2, RPA1, YWHAQ, ATP4A, env, PGRMC1, UBL4A, KLK10, SERPINF2, ATF2, CASP8, CANX, VKORC1, nef, APP, Htt, PTPLB, FIS1, MYH10, HLA-A, BCL2L1, ACTG1, DERL1, BCAP29, BFAR, SEC61A1, TRAM1, SEC61B, BCAP31, RNF5, LMAN1, CFTR, Copa
Protein Size: 246

Molecular Weight: 28 kDa

Gene ID: 10134

NCBI Accession: NM_005745, NP_005736

UniProt: P51572

Pathways: Positive Regulation of Endopeptidase Activity