MTA3 antibody (C-Term)

Catalog No. ABIN2783072

This anti-MTA3 antibody is a Rabbit Polyclonal antibody detecting MTA3 in WB. Suitable for Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for MTA3 antibody (C-Term) (ABIN2783072)

Target: MTA3 (Metastasis Associated 1 Family, Member 3 (MTA3))

Reactivity: Human, Mouse, Rat, Cow, Horse, Rabbit, Dog, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MTA3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MTA3 Antibody

Binding Specificity: C-Term

Sequence: TTEDPRVRSH VSRQAMQGMP VRNTGSPKSA VKTRQAFFLH TTYFTKFARQ

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against MTA3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MTA3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 515 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for MTA3

Target: MTA3 (Metastasis Associated 1 Family, Member 3 (MTA3))

Alternative Name: MTA3

Background: MTA3 plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels.
Alias Symbols: KIAA1266
Protein Interaction Partner: BCL6, NACC2, UBC, HNRNPA2B1, SOX2, HDAC2, HDAC1, MTA3, GATAD2B, RCOR3, GATAD2A, GSE1, RCOR1, HMG20A, HMG20B, MTA2, MBD2, CDK2AP1, RBBP7, RBBP4, CHD4, ARNT, CDK13, TFAP4, ELAVL1, KDM1A, KDM5B, RAD21, SMARCAD1, ESR1, JUN, ZFPM2, tat, CHD3, MBD3, GRB2,
Protein Size: 515

Molecular Weight: 59 kDa

Gene ID: 57504

NCBI Accession: NM_020744, NP_065795

Pathways: Chromatin Binding