Cofilin 2 antibody (C-Term)

Catalog No. ABIN2783370

This anti-Cofilin 2 antibody is a Rabbit Polyclonal antibody detecting Cofilin 2 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for Cofilin 2 antibody (C-Term) (ABIN2783370)

Target: Cofilin 2 (CFL2)

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cofilin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cofilin 2 Antibody

Binding Specificity: C-Term

Sequence: FWAPESAPLK SKMIYASSKD AIKKKFTGIK HEWQVNGLDD IKDRSTLGEK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against Cfl2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Cfl2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 166 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cofilin 2

Target: Cofilin 2 (CFL2)

Alternative Name: Cfl2

Background: Cfl2 controls reversibly actin polymerization and depolymerization in a pH -sensitive manner. It has the ability to bind G- and F-actin in a 1:1 ratio of cofilin to actin. It is the major component of intranuclear and cytoplasmic actin rods.
Alias Symbols: -
Protein Interaction Partner: CFTR,
Protein Size: 166

Molecular Weight: 19 kDa

Gene ID: 12632

NCBI Accession: NM_007688, NP_031714

UniProt: P45591

Pathways: Caspase Cascade in Apoptosis