CROT antibody (N-Term)

Catalog No. ABIN2783539

This anti-CROT antibody is a Rabbit Polyclonal antibody detecting CROT in WB. Suitable for Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Zebrafish (Danio rerio) and Saccharomyces cerevisiae.

Quick Overview for CROT antibody (N-Term) (ABIN2783539)

Target: CROT (Carnitine O-Octanoyltransferase (CROT))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Pig, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CROT antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CROT Antibody

Binding Specificity: N-Term

Sequence: MENQLAKSTE ERTFQYQDSL PSLPVPSLEE SLKKYLESVK PFANQEEYKK

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against CROT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CROT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 612 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CROT

Target: CROT (Carnitine O-Octanoyltransferase (CROT))

Alternative Name: CROT

Background: Carnitine octanoyltransferase is a carnitine acyltransferase that catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. This provides a crucial step in the transport of medium- and long-chain acyl-CoA out of the mammalian peroxisome to the cytosol and mitochondria.Carnitine octanoyltransferase (EC 2.3.1.137) is a carnitine acyltransferase that catalyzes the reversible transfer of fatty acyl groups between CoA and carnitine. This provides a crucial step in the transport of medium- and long-chain acyl-CoA out of the mammalian peroxisome to the cytosol and mitochondria. See also CRAT (MIM 600184). Van der Leij et al. (2000) [PubMed 11001805] reviewed the function, structural features, and phylogenetics of human carnitine acyltransferase genes, including CROT.[supplied by OMIM].
Alias Symbols: COT
Protein Interaction Partner: UBC, ALB, PEX5, DSTN,
Protein Size: 612

Molecular Weight: 70 kDa

Gene ID: 54677

NCBI Accession: NM_021151, NP_066974

UniProt: Q9UKG9

Pathways: Monocarboxylic Acid Catabolic Process