QTRTD1 antibody (N-Term)

Catalog No. ABIN2783554

This Rabbit Polyclonal antibody specifically detects QTRTD1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Horse, Rabbit, Cow, Dog and Guinea Pig.

Quick Overview for QTRTD1 antibody (N-Term) (ABIN2783554)

Target: QTRTD1 (Queuine tRNA-Ribosyltransferase Domain Containing 1 (QTRTD1))

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Cow, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This QTRTD1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-QTRTD1 Antibody

Binding Specificity: N-Term

Sequence: YTKTGSAPHL THHTLHNIHG VPAMAQLTLS SLAEHHEVLT EYKEGVGKFI

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against QTRTD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human QTRTD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 415 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for QTRTD1

Target: QTRTD1 (Queuine tRNA-Ribosyltransferase Domain Containing 1 (QTRTD1))

Alternative Name: QTRTD1

Background: This gene encodes a subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine, and tyrosine. The encoded protein may play a role in the queuosine 5'-monophosphate salvage pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: FLJ12960
Protein Interaction Partner: SUMO2, UBC, SUMO1, NEDD8, ALB, WAC, UBD, ISG15,
Protein Size: 415

Molecular Weight: 47 kDa

Gene ID: 79691

NCBI Accession: NM_024638, NP_078914

UniProt: Q9H974

Pathways: Ribonucleoside Biosynthetic Process