CHST13 antibody (C-Term)

Catalog No. ABIN2783631

This Rabbit Polyclonal antibody specifically detects CHST13 in WB. It exhibits reactivity toward Human and Guinea Pig.

Quick Overview for CHST13 antibody (C-Term) (ABIN2783631)

Target: CHST13 (Carbohydrate (Chondroitin 4) Sulfotransferase 13 (CHST13))

Reactivity: Human, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST13 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHST13 Antibody

Binding Specificity: C-Term

Sequence: CHPCRLRYDV VGKFETLAED AAFVLGLAGA SDLSFPGPPR PRGAAASRDL

Predicted Reactivity: Guinea Pig: 77%, Human: 100%

Characteristics: This is a rabbit polyclonal antibody against CHST13. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CHST13

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 341 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHST13

Target: CHST13 (Carbohydrate (Chondroitin 4) Sulfotransferase 13 (CHST13))

Alternative Name: CHST13

Background: CHST13 catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage and is distributed on the surfaces of many cells and extracellular matrices. It transfers sulfate to the C4 hydroxyl of beta1,4-linked GalNAc that is substituted with a beta-linked glucuronic acid at the C-3 hydroxyl. C4ST3 transfers sulfate to the C-4 hydroxyl of beta-1,4-linked GalNAc flanked by GlcUA residues in chondroitin (Kang et al., 2002 [PubMed 12080076]).[supplied by OMIM].
Alias Symbols: C4ST3, MGC119278, MGC119279, MGC119281
Protein Size: 341

Molecular Weight: 39 kDa

Gene ID: 166012

NCBI Accession: NM_152889, NP_690849

UniProt: Q8NET6

Pathways: Glycosaminoglycan Metabolic Process