GUCA2A antibody (Middle Region)
Quick Overview for GUCA2A antibody (Middle Region) (ABIN2784089)
Target
See all GUCA2A AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- FAPIPGEPVV PILCSNPNFP EELKPLCKEP NAQEILQRLE EIAEDPGTCE
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Predicted Reactivity
- Cow: 83%, Guinea Pig: 77%, Horse: 85%, Human: 100%, Mouse: 91%, Pig: 82%, Rabbit: 83%, Rat: 100%, Sheep: 92%, Yeast: 90%
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Characteristics
- This is a rabbit polyclonal antibody against GUCA2A. It was validated on Western Blot.
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Purification
- Affinity Purified
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 115 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GUCA2A (Guanylate Cyclase Activator 2A (Guanylin) (GUCA2A))
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Alternative Name
- GUCA2A
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Background
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GUCA2A is an endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.
Alias Symbols: GUANYLIN, GUCA2, STARA, GCAP-I
Protein Interaction Partner: GUCY2C,
Protein Size: 115 -
Molecular Weight
- 12 kDa
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Gene ID
- 2980
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NCBI Accession
- NM_033553, NP_291031
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UniProt
- Q02747
Target
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