GABARAP antibody (N-Term)

Catalog No. ABIN2784489

The Rabbit Polyclonal anti-GABARAP antibody has been validated for WB. It is suitable to detect GABARAP in samples from Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Pig, Rabbit and Saccharomyces cerevisiae.

Quick Overview for GABARAP antibody (N-Term) (ABIN2784489)

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Cow, Dog, Pig, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABARAP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABARAP Antibody

Binding Specificity: N-Term

Sequence: KFVYKEEHPF EKRRSEGEKI RKKYPDRVPV IVEKAPKARI GDLDKKKYLV

Predicted Reactivity: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GABARAP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GABARAP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 117 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABARAP

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Alternative Name: GABARAP

Background: Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. GABA(A) receptor-associated protein (GABARAP) is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ25768, MGC120154, MGC120155, MM46, ATG8A
Protein Interaction Partner: MUL1, UBC, SQSTM1, TAX1BP1, NBR1, ATG101, ATG13, SRPK2, SRPK1, MAPK15, MLH1, BNIP3L, KATNB1, RB1CC1, ULK2, ULK1, OPTN, TBC1D25, DVL2, ATG7, FKBP4, MAP1LC3C, DYX1C1, NCOA7, MAP1LC3B, TBC1D15, ATG3, PI4K2A, ANKFY1, GABARAPL1, ATG4B, FNBP1, GABARAPL2, TECPR2
Protein Size: 117

Molecular Weight: 14 kDa

Gene ID: 11337

NCBI Accession: NM_007278, NP_009209

UniProt: O95166

Pathways: Autophagy