P2RY1 antibody (N-Term)

Catalog No. ABIN2784500

The Rabbit Polyclonal anti-P2RY1 antibody has been validated for WB. It is suitable to detect P2RY1 in samples from Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Horse, Dog and Zebrafish (Danio rerio). There is 1 publication available.

Quick Overview for P2RY1 antibody (N-Term) (ABIN2784500)

Target: P2RY1 (Purinergic Receptor P2Y, G-Protein Coupled, 1 (P2RY1))

Reactivity: Human, Rat, Mouse, Cow, Guinea Pig, Rabbit, Horse, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RY1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-P2RY1 Antibody

Binding Specificity: N-Term

Sequence: VAIWMFVFHM KPWSGISVYM FNLALADFLY VLTLPALIFY YFNKTDWIFG

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against P2RY1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human P2RY1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 373 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-P2RY1 antibody (ABIN2784500)

Dilip, Ishii, Imada, Wada-Kiyama, Kiyama, Miyachi, Kaneda: "Distribution and development of P2Y1-purinoceptors in the mouse retina." in: Journal of molecular histology, Vol. 44, Issue 6, pp. 639-44, (2013) (PubMed).

Target Details for P2RY1

Target: P2RY1 (Purinergic Receptor P2Y, G-Protein Coupled, 1 (P2RY1))

Alternative Name: P2RY1

Background: The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor functions as a receptor for extracellular ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. [provided by RefSeq, Jul 2008].
Alias Symbols: P2y1, P2Y1
Protein Interaction Partner: SLC9A3R2, SLC9A3R1, ADORA1,
Protein Size: 373

Molecular Weight: 42 kDa

Gene ID: 5028

NCBI Accession: NM_002563, NP_002554

UniProt: P47900

Pathways: Regulation of Carbohydrate Metabolic Process, Feeding Behaviour