ANP32B antibody (N-Term)

Catalog No. ABIN2784808

This Rabbit Polyclonal antibody specifically detects ANP32B in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Sheep, Rabbit and Zebrafish (Danio rerio).

Quick Overview for ANP32B antibody (N-Term) (ABIN2784808)

Target: ANP32B (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member B (ANP32B))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Sheep, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANP32B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ANP32B Antibody

Binding Specificity: N-Term

Sequence: GLTAEFVNLE FLSLINVGLI SVSNLPKLPK LKKLELSENR IFGGLDMLAE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ANP32B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANP32B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 251 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ANP32B

Target: ANP32B (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member B (ANP32B))

Alternative Name: ANP32B

Background: ANP32B is a multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. ANP32B is required for the progression from the G1 to the S phase. ANP32B is an anti-apoptotic protein which functions as a caspase-3 inhibitor. It has no phosphatase 2A (PP2A) inhibitor activity.
Alias Symbols: APRIL, PHAPI2, SSP29
Protein Interaction Partner: HUWE1, SDCBP, MEOX2, KPNA5, KPNA1, rev, GRPEL1, KIAA1279, ARPC2, ACTR2, ACTR3, ARPC1B, ARPC5, SH3GL1, RPA1, DHPS, CALR, BAG1, SMAD2, ICAM1, CD81, IGSF8, SOX2, VCAM1, UBC, SMARCD1, ITGA4, HNF4A, FN1, CSNK2A1, CDH1, APP, ELAVL1, SUMO2, PIDD1, UCHL5, CHAF1A,
Protein Size: 251

Molecular Weight: 29 kDa

Gene ID: 10541

NCBI Accession: NM_006401, NP_006392

UniProt: Q92688