EXOC5 antibody (N-Term)

Catalog No. ABIN2784822

This anti-EXOC5 antibody is a Rabbit Polyclonal antibody detecting EXOC5 in WB. Suitable for Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for EXOC5 antibody (N-Term) (ABIN2784822)

Target: EXOC5 (Exocyst Complex Component 5 (EXOC5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXOC5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-EXOC5 Antibody

Binding Specificity: N-Term

Sequence: ATKVCHLGDQ LEGVNTPRQR AVEAQKLMKY FNEFLDGELK SDVFTNSEKI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against EXOC5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human EXOC5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 708 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EXOC5

Target: EXOC5 (Exocyst Complex Component 5 (EXOC5))

Alternative Name: EXOC5

Background: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.
Alias Symbols: DKFZp666H126, HSEC10, PRO1912, SEC10, SEC10L1, SEC10P
Protein Interaction Partner: HDDC3, TXLNB, CCDC67, TTC23L, FRMD6, BRMS1L, CCDC102B, KXD1, RAB4B, RAB14, TNPO2, PYCARD, EDRF1, C9orf9, TXNL4A, EXOC5, RAB4A, PTK6, OAS1, MAGEA6, ENO2, BARD1, UBC, EGFR, ACTR3B, ADCK1, TBX21, SOX10, ICA1, CDH2, EXOC8, EXOC4, EXOC2, EXOC7, EXOC3, UBD, PRK
Protein Size: 708

Molecular Weight: 82 kDa

Gene ID: 10640

NCBI Accession: NM_006544, NP_006535

UniProt: O00471

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis