GABARAPL2 antibody (N-Term)

Catalog No. ABIN2784885

This Rabbit Polyclonal antibody specifically detects GABARAPL2 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Rabbit and Goat.

Quick Overview for GABARAPL2 antibody (N-Term) (ABIN2784885)

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse, Rabbit, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABARAPL2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABARAPL2 Antibody

Binding Specificity: N-Term

Sequence: KWMFKEDHSL EHRCVESAKI RAKYPDRVPV IVEKVSGSQI VDIDKRKYLV

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against GABARAPL2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GABARAPL2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 117 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABARAPL2

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Alternative Name: GABARAPL2

Background: GABARAPL2 belongs to the MAP1 LC3 family. It modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. The protein first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1.
Alias Symbols: ATG8, GATE-16, GATE16, GEF-2, GEF2, ATG8C
Protein Interaction Partner: GIMAP6, KRTAP10-9, KRTAP10-7, KIAA1958, CCDC155, FUNDC1, AHNAK2, TSR2, UBA5, CALCOCO1, AGTRAP, ARFGAP1, BCL2L13, SIK2, TBC1D9B, TNIP1, CALCOCO2, TBC1D5, SQSTM1, UBC, MLX, MAP1LC3B, WWOX, ATG4A, BNIP3L, SGTA, VAPA, CLN8, APP, ATG13, ULK2, ULK1, NBR1, TBC1D
Protein Size: 117

Molecular Weight: 14 kDa

Gene ID: 11345

NCBI Accession: NM_007285, NP_009216

UniProt: P60520

Pathways: Autophagy