DNAJB6 antibody (N-Term)

Catalog No. ABIN2784952

This Rabbit Polyclonal antibody specifically detects DNAJB6 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse, Saccharomyces cerevisiae and Zebrafish (Danio rerio).

Quick Overview for DNAJB6 antibody (N-Term) (ABIN2784952)

Target: DNAJB6 (DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Rabbit, Dog, Horse, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJB6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-DNAJB6 Antibody

Binding Specificity: N-Term

Sequence: PENKEEAERK FKQVAEAYEV LSDAKKRDIY DKYGKEGLNG GGGGGSHFDS

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against DNAJB6. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DNAJB6

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 326 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for DNAJB6

Target: DNAJB6 (DnaJ (Hsp40) Homolog, Subfamily B, Member 6 (DNAJB6))

Alternative Name: DNAJB6

Background: DNAJB6 is a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons.This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants, however, not all variants have been fully described.
Alias Symbols: DKFZp566D0824, DnaJ, FLJ42837, HHDJ1, HSJ-2, HSJ2, MGC1152, MGC117297, MRJ, MSJ-1, DJ4
Protein Interaction Partner: UBC, FAM96A, FAM96B, STIP1, STUB1, BAG2, BAG3, BAG4, MLF2, HSPA8, FKBP5, BAG1, TARDBP, SOX2, HDAC11, POLR1D, APP, BRMS1, CUL2, CUL3, EBNA-LP, PIK3CA, MYC, ALKBH1, HDAC4, TP63, TP73, TP53, SIRT2, HDAC6, USP8, KRT18,
Protein Size: 326

Molecular Weight: 36 kDa

Gene ID: 10049

NCBI Accession: NM_058246, NP_490647

UniProt: O75190