ABRA antibody (Middle Region)

Catalog No. ABIN2785041

This Rabbit Polyclonal antibody specifically detects ABRA in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for ABRA antibody (Middle Region) (ABIN2785041)

Target: ABRA (Actin-Binding rho Activating Protein (ABRA))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABRA antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ABRA Antibody

Binding Specificity: Middle Region

Sequence: QWADEHIQSQ KLNPFSEEFD YELAMSTRLH KGDEGYGRPK EGTKTAERAK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against ABRA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ABRA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 381 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ABRA

Target: ABRA (Actin-Binding rho Activating Protein (ABRA))

Alternative Name: ABRA

Background: ABRA acts as an activator of serum response factor (SRF)-dependent transcription possibly by inducing nuclear translocation of MKL1 or MKL2 and through a mechanism requiring Rho-actin signaling.
Alias Symbols: STARS
Protein Interaction Partner: ABLIM2, ABLIM3, ABLIM1, ACTA1, ACTB, ACTC1,
Protein Size: 381

Molecular Weight: 43 kDa

Gene ID: 137735

NCBI Accession: NM_139166, NP_631905

UniProt: Q8N0Z2

Pathways: Protein targeting to Nucleus