FBXO15 antibody (N-Term)

Catalog No. ABIN2785229

Product Details anti-FBXO15 Antibody

Target: FBXO15 (F-Box Protein 15 (FBXO15))

Binding Specificity: N-Term

Reactivity: Human, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO15 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QDKEAGYWKK EYITKQIASV KAALADILKP VNPYTGLPVK TKEALRIFGL

Predicted Reactivity: Cow: 79%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO15. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO15

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 434 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO15

Target: FBXO15 (F-Box Protein 15 (FBXO15))

Alternative Name: FBXO15 (FBXO15 Products)

Background: FBXO15 is the substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXO15, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: FBX15, MGC39671
Protein Interaction Partner: CRLS1, UBA7, UBC, ABCB1, SKP1,
Protein Size: 434

Molecular Weight: 49 kDa

Gene ID: 201456

NCBI Accession: NM_152676, NP_689889

UniProt: Q8NCQ5