FBXO15 antibody (N-Term)

Catalog No. ABIN2785229

This Rabbit Polyclonal antibody specifically detects FBXO15 in WB. It exhibits reactivity toward Human, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit and Cow.

Quick Overview for FBXO15 antibody (N-Term) (ABIN2785229)

Target: FBXO15 (F-Box Protein 15 (FBXO15))

Reactivity: Human, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO15 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXO15 Antibody

Binding Specificity: N-Term

Sequence: QDKEAGYWKK EYITKQIASV KAALADILKP VNPYTGLPVK TKEALRIFGL

Predicted Reactivity: Cow: 79%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against FBXO15. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FBXO15

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 434 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO15

Target: FBXO15 (F-Box Protein 15 (FBXO15))

Alternative Name: FBXO15

Background: FBXO15 is the substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.Members of the F-box protein family, such as FBXO15, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: FBX15, MGC39671
Protein Interaction Partner: CRLS1, UBA7, UBC, ABCB1, SKP1,
Protein Size: 434

Molecular Weight: 49 kDa

Gene ID: 201456

NCBI Accession: NM_152676, NP_689889

UniProt: Q8NCQ5