KLC3 antibody (Middle Region)

Catalog No. ABIN2785352

The Rabbit Polyclonal anti-KLC3 antibody has been validated for WB. It is suitable to detect KLC3 in samples from Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse and Rabbit.

Quick Overview for KLC3 antibody (Middle Region) (ABIN2785352)

Target: KLC3 (Kinesin Light Chain 3 (KLC3))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Cow, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KLC3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KLC3 Antibody

Binding Specificity: Middle Region

Sequence: LLCQNQGKFE DVERHYARAL SIYEALGGPH DPNVAKTKNN LASAYLKQNK

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 77%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against KLC3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human KLC3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 504 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for KLC3

Target: KLC3 (Kinesin Light Chain 3 (KLC3))

Alternative Name: KLC3

Background: KLC3 is a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.This gene encodes a member of the kinesin light chain gene family. Kinesins are molecular motors involved in the transport of cargo along microtubules, and are composed of two kinesin heavy chain (KHC) and two kinesin light chain (KLC) molecules. KLCs are thought to typically be involved in binding cargo and regulating kinesin activity. In the rat, a protein similar to this gene product is expressed in post-meiotic spermatids, where it associates with structural components of sperm tails and mitochondria.
Alias Symbols: KLC2, KLC2L, KLCt, KNS2B
Protein Interaction Partner: CENPP, CCDC36, CEP57L1, SPERT, KLC3, ZNF417, CCDC64B, ZNF572, BBS5, SNAP47, DTX2, USHBP1, IMP3, NECAB2, MBIP, WAC, ABI3, KDM1A, NDC80, PDE4DIP, STX11, TSNAX, TCF4, VPS52, QARS, KRT15, KRT13, GEM, CCNH, YWHAE, DYNC1I1, CUL2, CROCC, KIF5A, KIF5B, YWHAG, YWH
Protein Size: 504

Molecular Weight: 55 kDa

Gene ID: 147700

NCBI Accession: NM_177417, NP_803136

UniProt: Q6P597