ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 (ADAMTS18) (N-Term) antibody

Details for Product No. ABIN2785412, Supplier: Log in to see
Antigen
  • 9630038L21
  • ADAMTS21
  • E130314N14Rik
  • KNO2
  • RGD1560118
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
  • ADAM metallopeptidase with thrombospondin type 1 motif 18
  • ADAM metallopeptidase with thrombospondin type 1 motif, 18
  • Adamts18
  • ADAMTS18
Epitope
N-Term
14
10
3
3
2
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Rabbit, Rat (Rattus), Zebrafish (Danio rerio)
43
26
5
1
1
1
1
1
1
Host
Rabbit
40
3
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Western Blotting (WB)
40
29
8
6
3
Options
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Immunogen The immunogen is a synthetic peptide directed towards the N terminal region of human ADAMTS18
Blocking Peptide Blocking peptide for this product available: ABIN972910
Sequence FYQGFIRNDS SSSVAVSTCA GLSGLIRTRK NEFLISPLPQ LLAQEHNYSS
Predicted Reactivity Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%
Characteristics This is a rabbit polyclonal antibody against ADAMTS18. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ADAMTS18 (ADAMTS18 Antibody Abstract)
Background ADAMTS18 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined. This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.
Alias Symbols: ADAMTS21, KNO2
Protein Size: 1221
Molecular Weight 104 kDa
Gene ID 170692
NCBI Accession NM_199355, NP_955387
UniProt Q8TE60
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1221 AA

Restrictions For Research Use only
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-ADAM Metallopeptidase with thrombospondin Type 1 Motif, 18 (ADAMTS18) (N-Term) antibody (ABIN2785412) WB Suggested Anti-ADAMTS18 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
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