STAMBP antibody (N-Term)

Catalog No. ABIN2785428

The Rabbit Polyclonal anti-STAMBP antibody has been validated for WB. It is suitable to detect STAMBP in samples from Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for STAMBP antibody (N-Term) (ABIN2785428)

Target: STAMBP (STAM Binding Protein (STAMBP))

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STAMBP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-STAMBP Antibody

Binding Specificity: N-Term

Sequence: SDHGDVSLPP EDRVRALSQL GSAVEVNEDI PPRRYFRSGV EIIRMASIYS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against STAMBP. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human STAMBP

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 424 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for STAMBP

Target: STAMBP (STAM Binding Protein (STAMBP))

Alternative Name: STAMBP

Background: Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. STAMBP binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
Alias Symbols: AMSH, MGC126516, MGC126518
Protein Interaction Partner: CHMP1B, CHMP3, GRB2, UBC, TNFRSF1A, GJA1, MAP3K2, VAMP8, SUMO1, NEDD8, CLTC, FDPS, STAM, STAM2, GRAP2, TRIP13, SPG7, CHMP1A, ITGA5, CYP2C9, NTPCR, CHMP5, SMAD7, SMAD6, PJA1, USP28, USP21, CHMP4B, AMN, CTNNBL1, UACA, CHMP4A, MAP2K5, ALAS1, CASR, UBE2S, TRA
Protein Size: 424

Molecular Weight: 48 kDa

Gene ID: 10617

NCBI Accession: NM_213622, NP_998787

UniProt: O95630