TSKS antibody (N-Term)

Catalog No. ABIN2785555

This anti-TSKS antibody is a Rabbit Polyclonal antibody detecting TSKS in WB and IHC. Suitable for Human, Mouse, Rat, Cow, Dog, Pig and Rabbit.

Quick Overview for TSKS antibody (N-Term) (ABIN2785555)

Target: TSKS (Testis-Specific serine Kinase Substrate (TSKS))

Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSKS antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TSKS Antibody

Binding Specificity: N-Term

Sequence: MASVVVKTIW QSKEIHEAGD TPTGVESCSQ LVPEAPRRVT SRAKGIPKKK

Predicted Reactivity: Cow: 86%, Dog: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rabbit: 79%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against TSKS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TSKS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 592 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for TSKS

Target: TSKS (Testis-Specific serine Kinase Substrate (TSKS))

Alternative Name: TSKS

Background: TSKS may play a role in testicular physiology, spermatogenesis or spermiogenesis. Expression of TSKS is highest in the testis and down-regulated in testicular cancer. The gene is localized to the region 19q13.3 among the related RAS viral oncogene homolog (RRAS) and interferon regulatory factor 3 (IRF3) genes, which are both involved in tumorigenesis pathways and progression.This gene may play a role in testicular physiology, spermatogenesis or spermiogenesis. Expression of the encoded protein is highest in the testis and down-regulated in testicular cancer. The gene is localized to the region 19q13.3 among the related RAS viral oncogene homolog (RRAS) and interferon regulatory factor 3 (IRF3) genes, which are both involved in tumorigenesis pathways and progression.
Alias Symbols: TSKS1, TSSKS, STK22S1
Protein Interaction Partner: PPP1CA, SF3A3, SF3A1, USP10, APP, TSSK2,
Protein Size: 592

Molecular Weight: 65 kDa

Gene ID: 60385

NCBI Accession: NM_021733, NP_068379

UniProt: Q9UJT2

Pathways: Toll-Like Receptors Cascades