FLII antibody (Middle Region)

Catalog No. ABIN2785799

The Rabbit Polyclonal anti-FLII antibody has been validated for WB and IHC. It is suitable to detect FLII in samples from Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio) and Guinea Pig.

Quick Overview for FLII antibody (Middle Region) (ABIN2785799)

Target: FLII (Flightless I Homolog (FLII))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Zebrafish (Danio rerio), Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLII antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-FLII Antibody

Binding Specificity: Middle Region

Sequence: LAEDILNTMF DTSYSKQVIN EGEEPENFFW VGIGAQKPYD DDAEYMKHTR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Characteristics: This is a rabbit polyclonal antibody against FLII. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FLII

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1269 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FLII

Target: FLII (Flightless I Homolog (FLII))

Alternative Name: FLII

Background: FLII is a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. This gene is located within the Smith-Magenis syndrome region on chromosome 17.This gene encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. The protein is similar to a Drosophila protein involved in early embryogenesis and the structural organization of indirect flight muscle. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLI, FLIL, Fli1, MGC39265
Protein Interaction Partner: UBC, SUMO2, C14orf166, RTCB, IGF2BP3, PDCD6, LRRFIP1, EIF2B3, RPL27, RFC4, RFC2, PRKDC, NMT1, HNRNPM, MRE11A, KRT18, DHX9, DDX1, PAN2, HSP90AA1, FMNL1, BRCA1, EIF1AX, DGCR8, FBXO25, LRRFIP2, MYD88, ESR1, ACTL6A, GRIP1, CARM1, TRAIP, PRMT1, OPTN, DLST, ACT
Protein Size: 1269

Molecular Weight: 145 kDa

Gene ID: 2314

NCBI Accession: NM_002018, NP_002009

UniProt: Q13045