Glutaredoxin 1 antibody (N-Term)

Catalog No. ABIN2785807

The Rabbit Polyclonal anti-Glutaredoxin 1 antibody has been validated for WB. It is suitable to detect Glutaredoxin 1 in samples from Human, Mouse, Rat, Cow, Rabbit, Sheep, Guinea Pig, Horse, Dog and Zebrafish (Danio rerio).

Quick Overview for Glutaredoxin 1 antibody (N-Term) (ABIN2785807)

Target: Glutaredoxin 1 (GRX1)

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Sheep, Guinea Pig, Horse, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glutaredoxin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glutaredoxin 1 Antibody

Binding Specificity: N-Term

Sequence: IKQGLLEFVD ITATNHTNEI QDYLQQLTGA RTVPRVFIGK DCIGGCSDLV

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against GLRX. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLRX

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 106 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Glutaredoxin 1

Target: Glutaredoxin 1 (GRX1)

Alternative Name: GLRX

Background: GLRX has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. It reduces low molecular weight disulfides and proteins.
Alias Symbols: GRX, GRX1, MGC117407
Protein Interaction Partner: UBC, MMP23B, CASP3, AQP5, GOT2, NFIC, MAP3K5, PTPN1, ATP7B, ATP7A,
Protein Size: 106

Molecular Weight: 12 kDa

Gene ID: 2745

NCBI Accession: NM_002064, NP_002055

UniProt: P35754

Pathways: Cell RedoxHomeostasis