HSPE1 antibody (Middle Region)
Quick Overview for HSPE1 antibody (Middle Region) (ABIN2785819)
Target
See all HSPE1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Middle Region
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Sequence
- GKGGEIQPVS VKVGDKVLLP EYGGTKVVLD DKDYFLFRDG DILGKYVD
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Predicted Reactivity
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%
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Characteristics
- This is a rabbit polyclonal antibody against HSPE1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human HSPE1
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
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Comment
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Antigen size: 102 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- HSPE1 (Heat Shock 10kDa Protein 1 (Chaperonin 10) (HSPE1))
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Alternative Name
- HSPE1
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Background
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HSPE1 is a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner.
Alias Symbols: CPN10, GROES, HSP10, EPF
Protein Interaction Partner: UBC, MDM2, THOP1, TALDO1, RBBP7, PTMS, IDH1, DCK, ADSS, CHMP4A, CBX3, WDR1, HSPD1, HCVgp1, VCAM1, STK3, ITGA4, FN1, ATF2, VCP, MPI, HSPA9, CDK2, LRIF1, ZHX1, C14orf1, UNC119, CRMP1, CASP3, GBP2, TLE1, SAT1, EEF1A1, APLP1, ALDH2, DSTYK,
Protein Size: 102 -
Molecular Weight
- 11 kDa
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Gene ID
- 3336
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NCBI Accession
- NM_002157, NP_002148
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UniProt
- P61604
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Pathways
- Positive Regulation of Endopeptidase Activity
Target
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