GRK5 antibody (Middle Region)

Catalog No. ABIN2785866

This Rabbit Polyclonal antibody specifically detects GRK5 in WB and IHC. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio), Rabbit and Saccharomyces cerevisiae.

Quick Overview for GRK5 antibody (Middle Region) (ABIN2785866)

Target: GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))

Reactivity: Human, Mouse, Rat, Cow, Dog, Horse, Guinea Pig, Zebrafish (Danio rerio), Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRK5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-GRK5 Antibody

Binding Specificity: Middle Region

Sequence: FYAAEILCGL EDLHRENTVY RDLKPENILL DDYGHIRISD LGLAVKIPEG

Predicted Reactivity: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Yeast: 79%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against GRK5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GRK5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 590 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GRK5

Target: GRK5 (G Protein-Coupled Receptor Kinase 5 (GRK5))

Alternative Name: GRK5

Background: GRK5 is a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs).This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. It has also been shown to play a role in regulating the motility of polymorphonuclear leukocytes (PMNs). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: GPRK5
Protein Interaction Partner: TBXA2R, USP47, C1QBP, YWHAB, XRCC5, UBTF, UBC, TUFM, NR2F1, TCOF1, SRPK1, SPTBN1, SPTAN1, SMARCA1, SKP1, SRSF1, RPL4, RPL3, RBMS1, PSMD11, PSMD2, PSMC6, PSMC2, PSMC1, PRKDC, PPP2R2A, PNN, PIP4K2A, PIP, NFIB, NCL, NCBP1, MYO9B, MYO1C, MYH10, MYH9, MYCN, MA
Protein Size: 590

Molecular Weight: 68 kDa

Gene ID: 2869

NCBI Accession: NM_005308, NP_005299

UniProt: P34947

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling