Histone H1 antibody (N-Term)

Catalog No. ABIN2785869

This Rabbit Polyclonal antibody specifically detects Histone H1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow and Guinea Pig.

Quick Overview for Histone H1 antibody (N-Term) (ABIN2785869)

Target: Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Histone H1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Histone H1 Antibody

Binding Specificity: N-Term

Sequence: IQAEKNRAGS SRQSIQKYIK SHYKVGENAD SQIKLSIKRL VTTGVLKQTK

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against H1F0. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human H1F0

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 194 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Histone H1

Target: Histone H1 (H1F0) (H1 Histone Family, Member 0 (H1F0))

Alternative Name: H1F0

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H1F0 gene is intronless and encodes a member of the histone H1 family.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: H10, H1FV, MGC5241
Protein Interaction Partner: UBC, LIN28A, POP1, PRKRA, SUZ12, EED, RNF2, PARK2, ERCC8, PRKCB, CDK1, APP, CDK2, CDK4, CAND1, PfPK6, YWHAZ, CDK5, CCNE1, HDGF, Nedd4, NEDD4L, GRB2, YWHAQ, XBP1, IKBKG, NOA1, IPO7, RAD51B, KPNB1, IPO5, KPNA2,
Protein Size: 194

Molecular Weight: 21 kDa

Gene ID: 3005

NCBI Accession: NM_005318, NP_005309

UniProt: P07305