CMTR1 antibody (C-Term)

Catalog No. ABIN2786076

Product Details anti-CMTR1 Antibody

Target: CMTR1 (Cap Methyltransferase 1 (CMTR1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Dog, Guinea Pig, Rabbit, Cow, Horse, Rat, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CMTR1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YRLEEMEKIF VRLEMKIIKG SSGTPKLSYT GRDDRHFVPM GLYIVRTVNE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against FTSJD2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human FTSJD2

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CMTR1

Target: CMTR1 (Cap Methyltransferase 1 (CMTR1))

Alternative Name: FTSJD2 (CMTR1 Products)

Background: FTSJD2 is a S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to the 5'-cap structure of mRNAs. It methylates the ribose of the first nucleotide of a m7GpppG-capped mRNA to produce m7GpppNmp (cap1). Cap1 modification is linked to higher levels of translation. It may be involved in the interferon response pathway.
Alias Symbols: KIAA0082, MTr1, hMTr1, FTSJD2
Protein Interaction Partner: UBC, CUL3,
Protein Size: 835

Molecular Weight: 95 kDa

Gene ID: 23070

NCBI Accession: NM_015050, NP_055865

UniProt: Q8N1G2