CCNDBP1 antibody (Middle Region)

Catalog No. ABIN2786197

This Rabbit Polyclonal antibody specifically detects CCNDBP1 in WB. It exhibits reactivity toward Human, Mouse, Cow, Dog, Horse, Rabbit, Rat and Guinea Pig.

Quick Overview for CCNDBP1 antibody (Middle Region) (ABIN2786197)

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Reactivity: Human, Mouse, Cow, Dog, Horse, Rabbit, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CCNDBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CCNDBP1 Antibody

Binding Specificity: Middle Region

Sequence: NSAKLVSVLK KALEITKASH VTPQPEDSWI PLLINAIDHC MNRIKELTQS

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 85%, Rabbit: 100%, Rat: 92%

Characteristics: This is a rabbit polyclonal antibody against CCNDBP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CCNDBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 232 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CCNDBP1

Target: CCNDBP1 (Cyclin D-Type Binding-Protein 1 (CCNDBP1))

Alternative Name: CCNDBP1

Background: This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.
Alias Symbols: DIP1, GCIP, HHM
Protein Interaction Partner: TYMSOS, ZNRF2P1, C6orf226, FAM74A4, ZNF564, ZNF555, TMEM120B, TRAPPC5, RPL39L, ZNF670, NEURL3, ZNF697, ZNF439, C22orf23, ZGPAT, ZNF394, RBP5, FAM110A, THAP7, TTC23, DMRT3, ARHGAP22, CCDC146, ZNF490, THAP10, IMP3, FAM64A, ZNF581, MRPL15, CNNM3, SYF2, NUDCD
Protein Size: 232

Molecular Weight: 26 kDa

Gene ID: 23582

NCBI Accession: NM_037370, NP_411241