Glycerol Kinase antibody (Middle Region)

Catalog No. ABIN2786452

The Rabbit Polyclonal anti-Glycerol Kinase antibody has been validated for WB. It is suitable to detect Glycerol Kinase in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for Glycerol Kinase antibody (Middle Region) (ABIN2786452)

Target: Glycerol Kinase (GK)

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Glycerol Kinase antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Glycerol Kinase Antibody

Binding Specificity: Middle Region

Sequence: MAAGAAEGVG VWSLEPEDLS AVTMERFEPQ INAEESEIRY STWKKAVMKS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against GK. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GK

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 530 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Glycerol Kinase

Target: Glycerol Kinase (GK)

Alternative Name: GK

Background: The product of this gene belongs to the FGGY kinase family of proteins and encodes glycerol kinase. Glycerol kinase is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Defects in this gene are the cause of glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: GK1, GKD
Protein Interaction Partner: CLPTM1L, OPLAH, FBXO28, IPO13, RXRA, NR4A1, GPD1, EIF4G1, CYP3A4, APCS, AOX1, UBC,
Protein Size: 530

Molecular Weight: 58 kDa

Gene ID: 2710

NCBI Accession: NM_203391, NP_976325

UniProt: A6NJP5