GNB4 antibody (Middle Region)

Catalog No. ABIN2787271

The Rabbit Polyclonal anti-GNB4 antibody has been validated for WB. It is suitable to detect GNB4 in samples from Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for GNB4 antibody (Middle Region) (ABIN2787271)

Target: GNB4 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 4 (GNB4))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNB4 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GNB4 Antibody

Binding Specificity: Middle Region

Sequence: DGMCRQSFTG HVSDINAVSF FPNGYAFATG SDDATCRLFD LRADQELLLY

Specificity: Gene Symbol: GNB1, GNB2, GNB3
Protein Accession#: NP_002065, NP_005264, NP_002066
Nucleotide Accession#: NM_002074, NM_005273, NM_002075
Swissprot ID: P62873, P62879, P16520

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against all four GNB variants (1-4). It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GNB4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 340 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GNB4

Target: GNB4 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 4 (GNB4))

Alternative Name: GNB4

Background: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors.
Alias Symbols: -
Protein Interaction Partner: UBC, SUMO2, GNG8, GNG12, GNG2, GNG13, GNGT1, GNG11, GNG10, GNG7, GNG5, GNG4, GNG3, FBXO6, CDK18, ADRB2, PAN2, MTNR1A, ESR1, GNAI3, GNAI2, GNAI1, PDCL, CEP97, RGS6, Haus1, Haus4, Mau2, Trim69, Cdk1, MTNR1B, GNGT2, git11,
Protein Size: 340

Molecular Weight: 37 kDa

Gene ID: 59345

NCBI Accession: NM_021629, NP_067642

UniProt: Q9HAV0

Pathways: Myometrial Relaxation and Contraction