LATS1 antibody (Middle Region)

Catalog No. ABIN2787626

This Rabbit Polyclonal antibody specifically detects LATS1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Zebrafish (Danio rerio), Saccharomyces cerevisiae and Sheep.

Quick Overview for LATS1 antibody (Middle Region) (ABIN2787626)

Target: LATS1 (LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1))

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Cow, Zebrafish (Danio rerio), Saccharomyces cerevisiae, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LATS1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-LATS1 Antibody

Binding Specificity: Middle Region

Sequence: IPPQAKLSPE ASDLIIKLCR GPEDRLGKNG ADEIKAHPFF KTIDFSSDLR

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 83%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against LATS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LATS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1130 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LATS1

Target: LATS1 (LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1))

Alternative Name: LATS1

Background: The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late
Alias Symbols: WARTS, wts
Protein Interaction Partner: SPERT, KRT31, GOLGA2, FSD2, SSX2IP, CEP76, MOAP1, TFIP11, LDOC1, TRAF1, ITCH, HSP90AB1, AMOT, KIRREL, MOB1A, CEP192, LATS2, CEP152, CEP131, RAB35, SDCCAG3, YAP1, INADL, SEC16A, CCP110, TJP2, MAGI1, LIMD1, PKP4, OFD1, AMOTL1, CNTROB, MOB1B, LZTS2, MPP5, KI
Protein Size: 1130

Molecular Weight: 124 kDa

Gene ID: 9113

NCBI Accession: NM_004690, NP_004681

UniProt: O95835

Pathways: Regulation of Actin Filament Polymerization, Maintenance of Protein Location