FBXO27 antibody (Middle Region)

Catalog No. ABIN2787693

Product Details anti-FBXO27 Antibody

Target: FBXO27 (F-Box Protein 27 (FBXO27))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO27 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LDKFSAVPDP IPQWNNNACL HVTHVFSNIK MGVRFVSFEH RGQDTQFWAG

Predicted Reactivity: Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against FBXO27. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO27

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 283 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO27

Target: FBXO27 (F-Box Protein 27 (FBXO27))

Alternative Name: FBXO27 (FBXO27 Products)

Background: Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: FBG5, Fbx27
Protein Interaction Partner: CLN5, HSP90AA1, RBX1, CUL1, SKP1, ELAVL1, MGMT, STUB1,
Protein Size: 283

Molecular Weight: 31 kDa

Gene ID: 126433

NCBI Accession: NM_178820, NP_849142

UniProt: Q8NI29