FBXO27 antibody (Middle Region)

Catalog No. ABIN2787693

This Rabbit Polyclonal antibody specifically detects FBXO27 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for FBXO27 antibody (Middle Region) (ABIN2787693)

Target: FBXO27 (F-Box Protein 27 (FBXO27))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBXO27 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-FBXO27 Antibody

Binding Specificity: Middle Region

Sequence: LDKFSAVPDP IPQWNNNACL HVTHVFSNIK MGVRFVSFEH RGQDTQFWAG

Predicted Reactivity: Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 83%

Characteristics: This is a rabbit polyclonal antibody against FBXO27. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO27

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 283 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for FBXO27

Target: FBXO27 (F-Box Protein 27 (FBXO27))

Alternative Name: FBXO27

Background: Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1, MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Alias Symbols: FBG5, Fbx27
Protein Interaction Partner: CLN5, HSP90AA1, RBX1, CUL1, SKP1, ELAVL1, MGMT, STUB1,
Protein Size: 283

Molecular Weight: 31 kDa

Gene ID: 126433

NCBI Accession: NM_178820, NP_849142

UniProt: Q8NI29