ATG16L1 antibody (N-Term)

Catalog No. ABIN2787879

This Rabbit Polyclonal antibody specifically detects ATG16L1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Guinea Pig and Zebrafish (Danio rerio).

Quick Overview for ATG16L1 antibody (N-Term) (ABIN2787879)

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Guinea Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG16L1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ATG16L1 Antibody

Binding Specificity: N-Term

Sequence: EYDALQITFT ALEGKLRKTT EENQELVTRW MAEKAQEANR LNAENEKDSR

Predicted Reactivity: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against ATG16L1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ATG16L1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 523 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ATG16L1

Target: ATG16L1 (ATG16 Autophagy Related 16-Like 1 (ATG16L1))

Alternative Name: ATG16L1

Background: Autophagy is the major intracellular degradation system delivering cytoplasmic components to lysosomes, and it accounts for degradation of most long-lived proteins and some organelles. Cytoplasmic constituents, including organelles, are sequestered into double-membraned autophagosomes, which subsequently fuse with lysosomes. ATG16L1 is a component of a large protein complex essential for autophagy.
Alias Symbols: APG16L, ATG16L, FLJ00045, FLJ10035, FLJ10828, FLJ22677, IBD10, WDR30, ATG16A
Protein Interaction Partner: WIPI2, RB1CC1, DEDD2, TRAF3IP3, NOD2, TMEM59, TLR2, SUMO2, ATG13, ATG5, ULK1, UBC, TNK2, SYNPO2, ATG12, NOD1, WDFY3, APP, RAB33B, RAB35, RAB3D, RAB33A, HSPA4, FCGRT, CLTC, AP2M1, ELAVL1, MAP1LC3C, MAP1LC3B, ATG3, CCT2, CCT7, AGPS, GAN, CCT3, SNAPC4, ATG16
Protein Size: 523

Molecular Weight: 58 kDa

Gene ID: 55054

NCBI Accession: NM_001190266, NP_001177195

UniProt: Q53SV2

Pathways: Autophagy