Neuropilin 1 antibody (N-Term)

Catalog No. ABIN2787936

The Rabbit Polyclonal anti-Neuropilin 1 antibody has been validated for WB. It is suitable to detect Neuropilin 1 in samples from Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse and Zebrafish (Danio rerio).

Quick Overview for Neuropilin 1 antibody (N-Term) (ABIN2787936)

Target: Neuropilin 1 (NRP1)

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neuropilin 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Neuropilin 1 Antibody

Binding Specificity: N-Term

Sequence: FNPHFDLEDR DCKYDYVEVF DGENENGHFR GKFCGKIAPP PVVSSGPFLF

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against NRP1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NRP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 644 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Neuropilin 1

Target: Neuropilin 1 (NRP1)

Alternative Name: NRP1

Background: NRP1 is a membrane-bound coreceptor to a tyrosine kinase receptor for both vascular endothelial growth factor (VEGF, MIM 192240) and semaphorin (see SEMA3A, MIM 603961) family members. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.
Alias Symbols: BDCA4, CD304, DKFZp686A03134, DKFZp781F1414, NP1, NRP, VEGF165R
Protein Interaction Partner: UBC, VEGFA, TGFBR3, TGFBR2, TGFBR1, L1CAM, PDGFB, PLVAP, CSNK2A2, RPL27, SRRM1, PLXNA1, GIPC1, SEMA3A, SEMA3C, NRP2, NRP1, VEGFB, SEMA3B, SEMA3F, PGF, KDR, FLT1, FGF4, FGF7, FGFR1, FGF2, FGF1, HGF, PLXND1,
Protein Size: 644

Molecular Weight: 72 kDa

Gene ID: 8829

NCBI Accession: NM_001024628, NP_001019799

Pathways: Regulation of Cell Size, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, VEGFR1 Specific Signals