COL9A1 antibody (N-Term)

Catalog No. ABIN2788309

This Rabbit Polyclonal antibody specifically detects COL9A1 in WB. It exhibits reactivity toward Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for COL9A1 antibody (N-Term) (ABIN2788309)

Target: COL9A1 (Collagen, Type IX, alpha 1 (COL9A1))

Reactivity: Human, Mouse, Rat, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL9A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COL9A1 Antibody

Binding Specificity: N-Term

Sequence: GADGLTGPDG SPGSIGSKGQ KGEPGVPGSR GFPGRGIPGP PGPPGTAGLP

Predicted Reactivity: Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 79%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against COL9A1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human COL9A1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 678 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for COL9A1

Target: COL9A1 (Collagen, Type IX, alpha 1 (COL9A1))

Alternative Name: COL9A1

Background: This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20 % ) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.
Alias Symbols: DJ149L1.1.2, EDM6, FLJ40263, MED, STL4
Protein Interaction Partner: COMP, MAG, COL2A1,
Protein Size: 678

Molecular Weight: 62 kDa

Gene ID: 1297

NCBI Accession: NM_078485, NP_511040

UniProt: A6NEQ6