IL-27 antibody (C-Term)

Catalog No. ABIN2788559

This anti-IL-27 antibody is a Rabbit Polyclonal antibody detecting IL-27 in WB. Suitable for Human.

Quick Overview for IL-27 antibody (C-Term) (ABIN2788559)

Target: IL-27 (IL27) (Interleukin 27 (IL27))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL-27 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL-27 Antibody

Binding Specificity: C-Term

Sequence: AQVSWPQLLS TYRLLHSLEL VLSRAVRELL LLSKAGHSVW PLGFPTLSPQ

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against IL27. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human IL27

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 243 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IL-27

Target: IL-27 (IL27) (Interleukin 27 (IL27))

Alternative Name: IL27

Background: The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).
Alias Symbols: IL-27, IL-27A, IL27p28, IL30, MGC71873, p28, IL27A
Protein Interaction Partner: IL27RA,
Protein Size: 243

Molecular Weight: 27 kDa

Gene ID: 246778

NCBI Accession: NM_145659, NP_663634

UniProt: Q8NEV9