Cathepsin G antibody (C-Term)

Catalog No. ABIN786341

The Rabbit Polyclonal anti-Cathepsin G antibody has been validated for WB. It is suitable to detect Cathepsin G in samples from Human, Rat and Guinea Pig.

Quick Overview for Cathepsin G antibody (C-Term) (ABIN786341)

Target: Cathepsin G (CTSG)

Reactivity: Human, Rat, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin G antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Cathepsin G Antibody

Binding Specificity: C-Term

Sequence: SYDPRRQICV GDRRERKAAF KGDSGGPLLC NNVAHGIVSY GKSSGVPPEV

Predicted Reactivity: Guinea Pig: 79%, Human: 100%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against CTSG. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 255 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Cathepsin G

Target: Cathepsin G (CTSG)

Alternative Name: CTSG

Background: The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
Alias Symbols: CG, MGC23078, CATG
Protein Interaction Partner: NOTCH2NL, KRT31, env, SERPINB4, ERBB2IP, PARP1, RAD21, PPBP, SERPINB13, F2RL2, CASP7, F2RL1, CXCL12, SELPLG, CAMP, SERPINA1, GP1BA, KNG1, F5, VCAM1, THBS1, F2R, SDC1, CXCR4, IGFBP3, SERPIND1, C3, LRP1, SERPINA3, AGT,
Protein Size: 255

Molecular Weight: 27 kDa

Gene ID: 1511

NCBI Accession: NM_001911, NP_001902

UniProt: P08311

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones