Chromosome 7 Open Reading Frame 20 (C7orf20) (N-Term) antibody

Catalog No. ABIN2788715

This Rabbit Polyclonal antibody specifically detects in WB. It exhibits reactivity toward Human, Mouse, Rat, Guinea Pig, Cow, Horse, Zebrafish (Danio rerio) and Dog.

Quick Overview for Chromosome 7 Open Reading Frame 20 (C7orf20) (N-Term) antibody (ABIN2788715)

Target: Chromosome 7 Open Reading Frame 20 (C7orf20)

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Horse, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Product Details

Binding Specificity: N-Term

Sequence: ASVEKGDYYE AHQMYRTLFF RYMSQSKHTE ARELMYSGAL LFFSHGQQNS

Predicted Reactivity: Cow: 85%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against GET4. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 327 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Chromosome 7 Open Reading Frame 20 (C7orf20)

Alternative Name: GET4

Background: GET4 is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.
Alias Symbols: CEE, CGI-20, TRC35, C7orf20
Protein Interaction Partner: HUWE1, PRKAB2, FAF1, VAPB, SGTA, UBC, RABEP2, LSM8, MTA2, CSTF2, FAF2, BAG6, UBL4A, VCP, EXOC2, SEC61B, TRA, AMFR, KEAP1, TMEM256, KIAA1377, ATP5H, KIFC2, EEF1G, UBAC2, SNCAIP, PLK1, PRKCSH, KAT5, TTR, PTMS, SOD2, CDKN1A, CAPNS1, WRAP73,
Protein Size: 327

Molecular Weight: 36 kDa

Gene ID: 51608

NCBI Accession: NM_015949, NP_057033

UniProt: Q7L5D6