Chromosome 7 Open Reading Frame 20 (C7orf20) (N-Term) antibody

Catalog No. ABIN2788715

Product Details

Target: Chromosome 7 Open Reading Frame 20 (C7orf20)

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Horse, Zebrafish (Danio rerio), Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB)

Sequence: ASVEKGDYYE AHQMYRTLFF RYMSQSKHTE ARELMYSGAL LFFSHGQQNS

Predicted Reactivity: Cow: 85%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rat: 93%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against GET4. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 327 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details

Target: Chromosome 7 Open Reading Frame 20 (C7orf20)

Alternative Name: GET4 (C7orf20 Products)

Background: GET4 is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.
Alias Symbols: CEE, CGI-20, TRC35, C7orf20
Protein Interaction Partner: HUWE1, PRKAB2, FAF1, VAPB, SGTA, UBC, RABEP2, LSM8, MTA2, CSTF2, FAF2, BAG6, UBL4A, VCP, EXOC2, SEC61B, TRA, AMFR, KEAP1, TMEM256, KIAA1377, ATP5H, KIFC2, EEF1G, UBAC2, SNCAIP, PLK1, PRKCSH, KAT5, TTR, PTMS, SOD2, CDKN1A, CAPNS1, WRAP73,
Protein Size: 327

Molecular Weight: 36 kDa

Gene ID: 51608

NCBI Accession: NM_015949, NP_057033

UniProt: Q7L5D6